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[Ala9]Autocamtide2

Name
[Ala9]Autocamtide2
Molecular structural formula
Purity
95%
CAS Number
167114-91-2
Formula
C64H116N22O19
MW
1497.74
Target
CaMK Autophagy
Sequence
Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Sequence Shortening
KKALRRQEAVDAL
InChIKey
VEQSFIGLQBPRPR-QXJRBMJXSA-N
References
[1]. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. [2]. Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca(2+) release events in a rodent model of early stage diabetes: The arrhythmogenic substrate. [3]. Intra-nucleus accumbens administration of the calcium/calmodulin-dependent protein kinase II inhibitor AIP induced antinociception in rats with mononeuropathy.
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Product details
Data download

Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.